The DB610 had the individual crankshaft centerlines about as close together as you're going to get with coupled/paired engines, regardless of the configuration (positioning of the engines).
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Another factor to consider, is the size of the coupler and it's interior components needed to transfer power from the engines to the drive shaft.
In the attached photo of the DB610, you can see the size of the coupler housing in relation to the engines and it's size was relevant to the gear sets as well as drive disconnects for each engine.