If you go back to my post #87 and look at the P-39's diagram, you'll see the subframe assembly that the cockpit attached to.
The cockpit subassembly would have added additional weight to the total airframe weight, but it also tied in with the airframe, adding additional strength.
As it is, removing the car doors and installing a conventional canopy wouldn't help the weight issue much, as the cockpit subassembly would still exist as a component.
Again, referring to the diagram, you can see how the cockpit is designed to be removed in it's entirety in order to perform extended maintenance