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Spitfire was 13% but since the wing had a long cord that meant the wing was still fairly thick in actual inches/cm. Mustang had thicker wing in percentage.
Now one can see that they didn't really redesign the wing to fit in the extra 1 or 2 guns on each side. That is to say they did not design a gun bay that would hold 4 guns like the Hurricane. They sort of just jammed the extra guns in-between the existing rib spacing and arranged the ammo to suit. This also spread the weight out along the wing and while it helped with the span loading it may not have helped the roll response any but then that last .303 gun is not very heavy.
If you are designing a totally new wing there is no reason to keep the original gun spacing to hold 6-8 .303s. Trying to fit Hispano guns in the wings get harder, not impossible but harder. Spanish did just stick Hispano guns in a 109 wing. They redesigned that area of the wing to hold the Hispano gun including fitting a new short spar or bulkhead to mount the gun after they made a rather large hole through the replacement spar.
Since you have to fit the guns outside the wheel wells actual space inside the wing starts to get tight.