Handling and climb were not that much affected, since it was most of the times 'item A out, install item B' procedure. However, speed was very much hurt when the 190F carried four wing racks and belly rack - a 35-40 km/h loss vs. 190A-6. Still can bag a mid-war Soviet fighter, or any 'frontline bomber' (Il-2, A-20, B-25 etc.) but will not cut it against the Typhoon, Tempest, Spitfire IX or XII, or any later US or Soviet fighter.
The 190G was considerably faster than the 190F on same power, due to having less racks and less guns (= lower drag). 190G-8 was also much lighter than F-8 or A-8, by 300 kg, all for clean condition.