SpicyJuan11
Senior Airman
Kind of depends on how much time you want to spend redesigning the whole thing. Trading three 1350hp engines that weigh around 13-1400lbs for two 22-2400hp engines that weigh around 2400lbs, shouldn't be too hard but then you done't get much, if any performance increase. You also have a bit of a problem if one quits.
Keeping 3 engines gives more performance but also increases the empty weight by well over 3000lbs. You aren't going to use Jumo 211 radiators to cool Ju 222 engines and you sure aren't going to use Jumo 211 propellers. If you use the extra power you are going to burn more fuel per mile/km. Payload is cut significantly. Now with the extra power you can certainly lift a bigger load but are the tires, landing gear, brakes up to it? Is the wing up to handling not only the extra weight but whatever extra speed you are using? and so on. Most passenger/cargo planes were built with much lower reserves of strength than Fighters or even bombers.
ANd do you really need a faster transport? If you go for the 66-7200hp installed power option is the plane now volume limited? Can lift more weight than the normal cargo items use up in volume?
Wait a second. How are you going to lose range with the 222's, didn't they have good fuel efficiency, wouldn't the removal of drag in the nose increase performance?