wuzak
Captain
I might be a little late on this but a while back we discussed the Mosquito performing a high altitude mission in the same capacity the B-17 and B-24 accomplished. Remember that if you're bombing with a precision optical bomb sight, you are commencing you're bomb run at speeds just above cruising and I think you're probably looking at about 250 mph maximum. I know somewhere on here we posted the Mosquito's bomb door operating speed and it wasn't as high as you would expect.
In the case with a Mosquito, it would have been the same sitting duck over target as any heavy, American or British were while bombing unescorted. The advantage "would have" been after the bomb run where the Mosquito "could have" used superior speed to depart the combat area.
Found it..
"bomb bay doors open 305 knots" = 340 mph - not bad providing you're able to accurately bomb at that speed at altitude depending on wind and other conditions.
Pilot's Notes - De Havilland Mosquito FB 6
Here's a Norden bombsight page that talks about some other bombs sights and setting speeds.
NORDEN BOMBSIGHT
That is still 150-180mph faster than the 8th AF heavies would have been travelling on the bomb run.
The vulnerability is also dependent on the time required to fly straight and level. I believe for the Norden that this time was significant.
The bombers would also be very vulnerable if they just flew in at the same level, at the same speed and on the same heading one after the other, particularly if there were many of them. It would give the flak gunners time to adjust their settings (I believe the Germans only used time fuzes for much of the war).