from Wiki so take it for what you think it is worth;
"On 27 May 264 Squadron claimed three He 111 and two damaged. On 28 May, shortly after take-off, 10 Defiants were attacked by about 30 Bf 109s – forming a circle, they claimed six German fighters for the loss of three Defiants. The Defiant was initially successful against enemy aircraft and its best day was 29 May, when No. 264 Squadron claimed
37 kills in two sorties:
19 Ju 87 Stukas, mostly picked off as they came out of their dives, nine
Messerschmitt Bf 110 twin-engined heavy fighters,
eight Bf 109s and a Ju-88; one Defiant gunner was lost after he bailed out, although the aircraft made it back to its base to be repaired.
[21] On 31 May, seven Defiants were lost in one day"
However
" Although 264 Squadron claimed 48 kills in eight days over Dunkirk, the cost was high with 14 Defiants lost. Actual German losses were no more than 12–15 enemy aircraft; the turret's wide angle of fire meant that several Defiants could engage the same target at one time, leading to multiple claims."
I am afraid the Defiants usefulness against the 110 is in some doubt. They did, undoubtedly, shoot down some. Whether it is at a 1 to 1 ratio or higher or lower is subject to question/further research. Like many air battles of limited numbers and duration the sample may be too small to draw a valid conclusion from.