"Naturally, once the war began, the Imperial Navy started losing pilots faster than they could be replaced. For example, the 29 pilots lost at Pearl Harbor represented more than a quarter of the annual crop. The battles of the next year led to the loss of hundreds of superb pilots."
Based on that I think no matter how good a fighter aircraft the IJN were able to operate, they doomed themselves from the start.
I was considering starting a thread, "Could the F4F have won the war without the F6F and F4U," but perhaps that question has just been answered.