I drove a Boss 302 with Aviation fuel in it when the leaded premium disappeared.
Ran just fine and was cheaper than adding Moroso power booster.
The mechanic at the airport said I should run a two to one mix, unleaded to leaded, or there abouts, as that would save money and on the street was all it really needed.
So I would go out about once every two or three weeks and top off what ever amount was in the tank with aviation gasoline.
He used to fill it up for me but the airport authority said he should not be doing that so after a while all he could do was turn the pump on.