I thought the 110's job was to range ahead of its own bombers and clearing the path of enemy fighters ?
It had several jobs. I think Rudiger Kosn lists them in his Book "The German Fighter"
1 Range ahead of own bombers to attack rising enemy fighters.
2 Strafe up enemy fighters and air defenses on the ground before they can takeoff.
3 Use its heavy fire power to bring down enemy bombers.
4 bad weather fighter ie operation in bad visibility (obviously night) with instruments and navigation aids.
5 the original zerstoerer spec called for bombs to be carried internally and a 3 man crew but Bf 110 could carry external bombs. The Bf 110 was actually a non conforming submission to the zerstoerer spec.
Because the RAF was using head on attacks on the bombers Goering had the Me 110 and Me 109 in close formation to thwart RAF head on attacks. Obviously the Me 110 would tend to win this type of duel but it made the Luftwaffe fighters very vulnerable particular the Bf 110 which had slow acceleration compared to a single and not quite as good a maneuverability.
If used in the 'range ahead of own bombers' I imagine it was reasonably successful as it can have the tactical freedom of moving at a faster speed and is said to have a superior exchange ratio versus the British fighters. Bf 110 are less likely to be 'bounced' due to the observers eyes and if there are enough Bf 110 around they can support each other due to good radio communication. Down side their large size means they are seen earlier.
In a turning dog fight the British fighter would end up below the Bf 110 where the observer couldn't engage the attacking fighter. The heavy maneuvering preventing aiming or even reloading of magazines. The observer was helpless. The Me 210/410 was supposed to fix this with its hydraulically powered guns, ability to fire below.