From the mid-30s on German fighters used electrical solenoids to fire their fuselage mounted guns so 2, 3, or 4 made little difference. Contacts were mounted on the prop shaft which opened and closed. Closed sent a signal to the solenoid which pulled the trigger. The guns were actually being fired in a semi-auto manner, i.e. one trigger pull one shot. The guns had to fire from the closed breech position and be mounted close to the prop. The working of the bolt took time as did the bullets flight time to the prop so the gun was often told to fire when it could not. Thus a second gun was used to increase the rate of fire. A third would increase this even more but space was not available. As aircraft became metal and even armoured and speed increased it became very difficult for two fuselage mounted guns firing rifle calibre ammunition to bring down the new monoplanes or the even bigger and heavier bombers. The monoplane's single much more rigid wing was an ideal spot to mount true machine guns which could be harmonized to produce a fairly narrow cone of fire. The larger wings offered more space for more guns thus the fighter delivered more weight of fire.
Only the UK and Soviet Union made use of the Contra-rotating props.