The P-38 is a really odd case.
Because of the problems with the P-39 and P-40 (single speed supercharger and weight) there was no quick fix for them and perhaps the "planners" thought that it easier to just transition to the P-47 instead.
Timing is critical here as an Allison powered P-51 doesn't do much for the USAAC and the Merlin powered P-51 doesn't start planning until summer of 1942.
P-47 has troubles (not the lack of drop tanks, that is in 1943) in 1942. They build 171 P-47Bs and NONE are sent overseas and the first P-47C rolls out of the factory Sept 14th 1942.
But this is two weeks after there are 164 P-38s in England (most will be sent to North Africa in Nov/Dec.
This leaves the P-38 as the ONLY high altitude fighter in the US army inventory (or likely to be) for the rest of 1942 and the start of 1943.
US training is kind of strange. They are giving the pilots a good amount of hours in the first 3 phases of training but not enough training on operational types. And 15-20 hours in a P-40 doesn't do a lot of good when a pilot is posted to a P-38 squadron. There were only a handful of 2 seat P-38 trainers (2 ?) and those were converted Ls in 1944 or 1945.
Power ratings are all over the place. On the Fs and Gs the intercoolers were not good enough to maintain military power above 15,000ft and according to some manuals WER was never allowed. I think the Hs were the same. This could be questionable in the Pacific. If you are not operating at 15,000ft you may not have a problem? But if you are you don't have the 1325 or 1425hp available that you have lower down. Once the J's show up in late 1943 you have 1425hp to over 25,000ft and even to 29,000ft depending on RAM. You have 1600hp WER at 25,800 with no ram and over 28,000ft with ram.
Between the engines, intercoolers, Turbos (B-13s and B-33s), turbo controllers, generator problems and the dive flaps and ailerons there were quite a number of things going on with the P-38s. Not helped by the training by the USAAC.
Not only were the recommendations for cruise faulty for range, they were the opposite of what was needed for fast throttle response if jumped. Using low boost and high rpm meant that the turbos were spooled down and they took a while to spool up to make combat power. The engines were also running cool or cold, not a big problem in the Pacific, more of a problem over Europe. But if you are not cruising fast the props may also be pitched wrong. Even if the engine is making about the same power, when at low rpm and higher boost the turbos are spinning faster and and if the pilot jams the throttles forward he is going to get more power right away. Props may be running in coarser pitch.
This was a self inflected wound that was the Responsibility of the US Army. THEY knew better than either Lockheed or Allison on how to operate the engines.
One thing that P-38 Pilots and crews did was leave about 800 rounds of .50 cal at home. The Ammo cans would hold 500 rounds per gun (about 38 seconds worth) and the 20mm gun ran out at about 15 seconds. 300 rounds would last 23-24 seconds and save about 240-250lbs.
Please note that P-38 with 300rpg has about 2.4 times the ammo that a Ki-43 does and that is the 20mm jams on the first shot.
P-38s sucked fuel but they could carry a lot and they could fly further when the drop tanks were empty than the P-39 and P-40 could, they were faster (a little bit), they could climb better and they were better at altitude. In late 1942, most of 1943 and into early 1944 what else did the US Army have that was any better in quantities in the Pacific?
For new members there is quite a collection of manuals in the technical section which is organized by nations.
ww2aircraft.net
Wartime manuals may misprints and/or revisions.