One issue with the mid engine configuration is the weight and complexity of the extension shaft. One has to route it below the pilot and employ careful engineering to avoid torsional resonances. There is a flexible coupling at the engine, ball bearings to support the shaft near its middle and separate arrangements for providing oil to the gearbox, which is located behind the propeller. All this made for a very noisy cockpit.
Other aircraft designs depending on extension shafts often had problems with vibrations - the XB-35 comes to mind.
Other aircraft designs depending on extension shafts often had problems with vibrations - the XB-35 comes to mind.