HAD the Mosquito used nitrous oxide (Rolls Royce did experiment with it) the Mosquito could have flown even higher and faster
So a plane with 50-70 examples built is a contender for best medium bomber or WW II?
This is fantasy, just adding black crosses to a plane that didn't fly in black cross publications doesn't change the laws of physics. A three ton bomb load isn't much in strategic terms, taking three tons of bombs to 48,000 ft is a dream with 1944 piston engine tech. You cannot hit anything dropping a dumb bomb from 48,000 ft over Europe and no guided bomb could either.
The Ju 388 with BMW 801TJ-1 engines had a service ceiling of 44000ft and in fact managed 46000ft. The Ju 488, which added an additional pair of engines and wing roots plugged in to the Ju 388 wing had lower wing loading, higher aspect ratio etc.
You should study the BMW 801TJ. Unlike most turbo charged engines it retained its two speed supercharger and added a large turbo charger with a very significant intercooler on top. Hence its critical altitude was very high, competitive with the R3350 at very high altitude.