Was +25psi the maximum any Merlin was cleared for. I find it amazing how engineers and chemists managed to take an engine from +3 (iirc) to +25 in such a short time
The merlin didn't have a particularly high compression ratio, it was only 6:1. 25psi relative is 39 psi absolute. The Germans would have referred to this as 2.785 ata ie atmospheres or BAR the US as 83.57 inches of mercury.
As fuels and spark plugs improved there was considerable scope especially with the use of inter cooling.
The low compression ratio has a considerable cost in power and efficiency though it does allow higher supercharging pressure with some recovery in the form of jet thrust from the high pressure. The inter cooler also allows higher boost though again it is throwing away energy.
By contrast the DB605DC had a compression ratio of 8.5:1. It reached boosts of 1.98 ata (about 14psi) using C3 fuel plus MW50. C3 fuel was equal to about 100/130 and I assume c3+mw50 was almost equal to 100/150
If you multiply 1.980 x 8.5 you get 17 for Daimler Benz engine
If you multiply 2.785 x 6.0 you get 16.71. For merlin engine.
The construction of the DB without head bolts allowed a larger volume without much weight increase though its RPM was less.
The Packard Merlin in the P-51H did use 100/150 plus ADI water injection though the British didn't seem too interested in ADI on the merlin.
US P-51D and H were flown at 90" Hg which is 3 Ata or 28 psig by using water injection Don't think they saw service.
The DB engines never saw service with inter coolers so and even the planed two stage versions of these engines added little in weight unlike the Merlin which added about 150kg.