DarrenW
Staff Sergeant
The Japanese went from a V-12 to a radial in going from the Ki-61 to the Ki-100, and they didn't seem to have much trouble.
The Ki-100 is a bad example. It was developed out of pure necessity and desperation which was never experienced by US aircraft manufactures. It's success could have went either way. In my opinion it garners a reputation that far exceeds it's virtues but that's another topic for another thread...
Though most likely doable it would have been a total waste of time, energy, and money to re-engine the P-39 with a Merlin, especially with far superior aircraft like the P-51B in need of them. By the summer of 1943 it was outclassed by all major US fighter types and Bell already had the much-improved P-63 in the works, so why even bother?