Kurt Tank chose the same workhorse Jumo 213 powerplant used in the Fw 190D. For the Ta 152H, he selected an uprated version, the Jumo 213E, equipped with a 2-stage, 3-speed mechanical supercharger and MW 50 engine boost. The MW 50 system used methanol-water mixture to boost engine output from 1,312 kw (1,750 hp) to 1,537 kw (2,050 hp) for short periods. Because of aluminum shortages, Focke-Wulf made the wing spars from steel and built the rear fuselage and empennage. The wing contained two steel spars. The front spar extended slightly beyond the landing gear attachment points but the rear spar spanned the entire wing. The wing twisted 3° from the root to the flap-aileron junction. This 'washout' prevented the ailerons from stalling before the center section. This allowed the pilot to maintain roll control during a stall. Armament consisted of one 30mm MK 108 cannon firing 90 rounds through the propeller hub and one 20mm MG 151 cannon firing 150-175 rounds from each wing root.
During the fall of 1944, Tank converted an existing Fw 190 prototype airframe (Werk-Nummer or serial number 0040) into the Ta 152H prototype. This aircraft and several other Ta 152 prototypes crashed early in the test program, due largely to intense pressure from the RLM to field production airplanes. Critical components suffered quality-control problems. Superchargers failed, pressurized cockpits leaked, the engine cooling system gave trouble, the landing gear failed to properly retract, and oil temperature gauges gave false readings. These problems, combined with Allied bombing attacks, which disrupted transportation and caused severe fuel shortages, slowed the whole program. Test pilots conducted just 31 hours of flight tests before full production started in November. By the end of January 1945 this figure had not climbed above 50 hours. This was not nearly enough time to refine subsystems and debug major components but production forged ahead.
Premature though it was, the Ta 152 had tremendous potential. Unlike the BV 155, a highly experimental, flying test-bed, Tank's design simply joined a powerful engine, already proven in the Fw 190D, to an existing airframe tweaked to perform at higher altitudes. The result was an airplane faster and more maneuverable than the P-51 Mustang and the P-47 Thunderbolt.
http://www.nasm.si.edu/research/aero/aircraft/focke_ta152.htm