I must admit that over the years I really egun to like the Bf-110.It´s much of a missed opportunity inmy eyes.
One of the prime mistakes is the comparably low wingloading of the model. For a twin this means that the plane could in theory outturn all contemporary Bf-109 variants and most of it´s opposition (safe the Hurricane and the Spit, the latter beeing an equal turner). In reality this doesn´t mean much because the time to bank is larger than all with the heavy weights of the engines buildt into the wings. It was even contra-effective because the good turn rate indirectly lead to the adoption of the defensive circle formation, once the initiative was gone.
However, the low wingloading also gave it a low speed take-off/landing performance and probably is the reason why the airframe could also accept much heavier payloads (up to 2 x 1000kg) and heavy upgrades later in the war.
A much more interesting proposal would be the Bf-110 with a smaller wing area. Something around 30 m^2 instead of the huge 38.4m^2. This would also allow for a direct comparison with the vaunted Focke Wulf 187 Falke.
It trades turn performance and takeoff performance for speed. In combination with the powerful frontal armement this would turn the Bf-110 into an uber-fighter with outstanding energy fighting abilities. It would also help to lower the bank times and roll rates.
I wonder why Messerschmidt didn´t adopted this when he was a forerunner of the high wingloaded design philosophy in the mid 30´s...
Somehow like this picture (not finetuned, it´s photoshop worked over!):