I'm a retired artilleryman by trade, so I know a bit about the actual effect of cannon shells. History actually tells us that aircraft cannon used against ground or naval targets were largely inneffective, and the 75mm is particularly puny. An aircraft can't carry the weight of a cannon, or absorb the recoil, to fire a shell large enough to really be effective.
If you want examples of what it takes and the limitations of cannon, read anything about employing submarine guns against naval targets. It sometimes took hundreds of hits by cannon far larger than any aircraft could carry to sink a ship. U.S. subs with 3 or 4 inch naval cannon were replaced by 5 inch cannon late in the war, but the whole idea of naval gunnery for subs was scrapped right after the war, due largely to ineffectivness.
Likewise, as good as 75mm B-25s were supposed to have been, why were they scrapped even before the war was over, and replaced with additional .50 Cal MGs?
The idea of aircraft cannon sounds cool, but it never really panned out. Otherwise, we'd have seen many more cannon armed aircraft.
What the man said.
The USAF and USN units using the B-25/PBJ in anti-shipping duties were far better off with skip-bombing and mast-height bombing. Even a small 250 lb bomb will do much more damage to any ship than a 14 lb shell the 75mm was firing. People might want to check the accounts of the Battle of Bismarck Sea (Wikipedia article), to see how devastating such bombing tactics were against destroyers and merchant shipping. The skip-bombers were supported by fighters, heavy bombers and RAAFs torpedo bombers, the most of the sinks was accomplished by skip-bombers. The 75mm used against anything bigger than destroyer escort would just scratch the paint of the intended target, while the B-26 with 8-12 HMGs in the nose can also suppress most of the target's AAA gunners much better than it would be possible with only 4 HMGs.
75mm was also ineffective against the targets in revetments, and parachute bombs were excellent to take out the such protected targets. The RAF quickly 'forgot' the excellent, high RoF Molins gun, and issued rockets to it's Mosquitoes.