I wonder why the P-51A had such a relatively poor combat history. Not terrible, mind you, but the fact that they were routinely coming out on the losing end of engagements with Ki-43s over China, Burma and India indicates that there was some kind of problem there.
So I don't pretend to be so well informed by this that I would defend my position vociferously, but from what I understand the P-51A pilots in CBI were largely inexperienced and used poor tactics. One story I am familiar with (hopefully it's even true) is the commander of one squadron of P-51A's getting shot down in his first mission there and when the Japanese pilot was later shot down himself, captured and interrogated he expressed puzzlement over why his victim had not just dived away instead of getting into a turning battle which he wasn't going to win. The tactics a P-51 would have to use vs those Japanese fighters are essentially the same as for the P-40 - it has pretty much the same advantages, it's just those advantages are bigger. If you play to your opponent's strengths, however, the outcome is not going to be good, regardless of your own strengths in other areas.