The MkVII with Merlin 60-70 series was the HF version of the Spit, Spitfire Mk VII Performance.Two comments on that - one thing I remember reading in pilot interviews about the HF wingtips, is that they disliked the pointed wingtips due to a very negative impact on roll rates. Which again makes me think of the Soviet complaints about the Hurricanes operating near Lenningrad.
I could be remembering this wrong but IIRC LF Spitfires were not doing so well by 20,000 ft due to the engines (Merlin 45M or 50M) critical altitude.
For example this chart for a Spit VB with a Merlin 50M tops out at 350 mph and +15lb boost at just below 6,000 ft. By 20'000 ft it's down to 337 mph and +5 lb boost.
Compare this to a Spit V with a Merlin 45 making 372 mph at 20,000 ft with +9 lb boost.
The V's fitted with Merlin M series engines and clipped wings were LF versions developed to combat the FW190, the M series was purposely developed to give their best performance at low altitude.