Check out Australian Archives file MP450/1 123 which is a form of sales brochure and performance details of the Lancaster, along with a very detailed break down of component weights, see the engine section below.
The document is undated but the engine arrangements are "For example power unit installations are already designed, or are in the process of design to accommodate the following engines:- Four engined, Rolls Royce Merlin XX or Pratt and Whitney Twin Wasp or Bristol Hercules. Twin engined, Rolls Royce Vulture, Bristol Centaurus, Napier Sabre."
Engine weights (4 engines and propellers) are given for three powerplant options
Merlin XX / Hercules VI / Twin Wasp S3C4-G /
5,200 / 5,900 / 4,800 / Take off power, BHP
5,720 / 7,460 / 5,940 / Engines - dry
9 / 10 / 10 / Air compressors
66 / 172 / 172 / Electric starters
10 / 0 / 0 / Hand turning gear
31 / 29 / 29 / Constant speed governor unit
16 / 16 / 16 / Vacuum pumps
168 / 120 / 113 / Air intakes, hot and cold
70 Auxiliary gear boxes
328 / 440 / 400 / Engine mountings
228 / 588 / 500 / Exhausts
1,282 / 0 / 0 / Cooling system and coolant
182 / 260 / 220 / Oil coolers and mounting
130 / 130 / 130 / Oil system, pipes, filters etc.
210 / 210 / 210 / Fuel system, pipes, filters etc.
200 / 200 / 200 / Engine controls
1,480 / 1,480 / 1,440 / Airscrews (Rotol)
140 / 160 / 140 / Fireproof bulkheads
520 / 360 / 340 / Engine cowling
0 / 160 / 140 / Additional cowling behind engines
0 / 220 / 200 / Cooling gills and mechanism
10,720 / 12,085 / 10,200 / Total engine and airscrew weight
No mention of the R-2800 in the file.