You're comparing 2 different operational theatres with very different operating environments which makes any direct correlations impossible, indeed it's irrelevant to the point you originally made.
I deliberately picked Tunisia because it's in the Mediterranean which is where you cited the P-38 would be the answer to the German fighters in that specific theatre. Clearly, the P-38 wasn't the answer in that theatre.
Your reply is mistaken in every respect.
1) The Bay of Biscay is not in the Mediterranean ocean.
2) In late 1942, No. 8 Staffel of JG 2 was based at Brest, France - not in Tunisia.
3) By his own account, Willi Reschke was based in Germany when JG 301 clashed with P-38s. By his own account, Horst Petzschler was based in Germany when he was shot down by a P-38.
I don't understand your comment about "operating environments". Coastal Command escort or fighter patrols was mainly low level work to protect the strikers and/or attack surface targets. Many pilots who flew both P-51 and P-38s with the 9th Air Force gave a frank comparison of the two aircraft in the fighter-bomber role - good luck finding even one who voted for the Mustang as better.
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