What job are you referring to?
The Me-110 was an aircraft in search of a purpose. It found that purpose during 1940 when the German night fighter force was created from scratch. But what was the purpose during 1937 when the Fw-187 was rejected in favor of the Me-110?
It was designed as a "destroyer". According to Luftwaffe doctrine it was supposed to clear a path for the bombers, and provide long range reconnaissance.
The original concept was (whatever DonL thinks) for the aircraft to be capable as a "light" bomber and was put out to tender in June 1934. The RLM's further requirement for a high speed bomber in early 1935 meant that the Bf 110 became more of a pure "zerstorer".
The Vultee report hit the nail on the head.
"The Messerschmitt Me 110 [sic] long-range fighter is an aircraft designed for blitzkrieg production as well as blitzkrieg warfare."
Clearing a path for the bombers,against a well organised and determined defence,equipped with competitive single engined fighters proved a bridge to far for the Bf 110.One area in which the type did well in the BoB was as a fighter bomber,attacking precision targets.
It did,as you say,form the backbone of the Nachtjagd for the rest of the war and proved quite capable as a fighter bomber on the Eastern Front. The Fw 187 couldn't have performed the first role and we'll never know how it would have done in the second.
It was the success of the Bf 110 in these unintended or secondary roles that militates against its cancellation in favour of another twin engined type.
Cheers
Steve