In theory yes but 1 v 1 air combat can be a rock-paper-scissors game. The RAAF test quoted earlier in this thread says the Spit.V(trop) they used in Australia had no great advantages over the tested A6M3 model 32 below 20,000ft.
The short range of the Spitfire was its biggest problem, In Burma the long range US airfield raids by P-51 and P-38's in early 1944 gave the JAAF no respite. The Beaufighter had the range to make the same long range raids but does not seem to have been used much for that?
This gives a good account of what happened.https://www.ozatwar.com/raf/spitfireoverdarwin.pdf