Wow, ton of good info in this thread. If you want to make best = most effective, you have to take mission capable rates, ease of use by pilot, survivability, etc into account. The Axis expended far greater effort in producing a dedicated bomber-killer, since their own airspace was (ahem) a target-rich environment. The 109 and the 190 each were pretty effective when equipped with multiple cannon and explosive shells. The 262 was a little too finicky in its handling (particularly the throttle), and required too much maintenance, and was too late in the war to prove itself. The 109 was good, especially at altitude, but didn't have enough power to overcome the additional armor and armament, and the 190 had enough power that all of the additional weight did not degrade performance as significantly as the 109.
A one-off quasi-prototype Hurricane equipped with cannons does not make the Hurricane the best bomber-destroyer of the entire war.