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If we are talking about the most effective interceptor in WW2 I pick the Me 262. It did not have the most kills of bombers but when it was operating it was almost unstoppable. It must have struck fear into the hearts of bomber crew in Europe. It would have effective against the B29 also. In Europe the interceptor that probably had the most kills would probably have been some model of the FW190 although Chris may have knowledge that shows the Bf109 to be supreme there. I don't know about overall WW2 numbers of bomber kills but in the Pacific I am sure that the Hellcat was the champion there with more bomber kills than any other AC(including kamikzes) and the Hellcat may be the bomber killing champion of the whole war.
I believe the Spitfire XIVe to be superior to the P-38L as an interceptor; it was just as quick to 20,000 feet (7 minutes for both, if I remember correctly) as the Lightning and would be more comfortable in and amongst the enemy escorts if they were encountered. The Spitfire had good firepower with 2x20mm Hispano Mk.II and two Browning M2 .50 cal. The only advantage of the P-38 would be the extended time in the battle, but this would not be as important in an intercept.
Hmmm... This kinda topic has been done so many times before, but I will chime in to get ur re-thread going some...
The FW-190 Dora is definitely one of the best performing a/c at 0 to 10,000 ft, with a SL top speed of 382.5 mph and 4,430 ft/min climb rate.
The FW-190 Dora is slightly faster and climbs slightly faster than the F4U-4. The same applies against the Tempest. (The Typhoon is too slow for comparison)
In 1941-42 the FW-190A is unrivalled in terms low alt performance.
According to my source the fastest US fighter at sea level was the F4u4. 380 mph. We know it was a formidable kamikaze interceptor as that AC was what the Navy loaded up with near the end when the kamikazes predominated. If it were eligible the F8F would have been a star because of it's high speed and rate of climb.