The design originally envisioned a more powerful engine. The -5 was all that was available when production started. The -43 was not a big improvement, so the whole B-26 program was always saddled with underpowered engines. That's a factor in aircraft development. You can't use what's not available. Then once production is in full swing, its hard to make major changes.
The B-26 involved so many untried systems that its not surprising that the early versions had a lot of issues. The Curtiss Electric prop was notorious for failing at high power.
The biggest problem was the flood of inexperienced pilots stuffed into them right out of flight school.
The 22nd BG and 28th BG, manned by crews trained prewar that flew them in action loved them. They were fast enough to outrun Zeroes, something the B-25 could not do.
The 22nd lost only a handful to fighters while flying the B-26, never more than one on a given mission, the 3rd BG flying B-25s at the same time lost five on one mission alone.
Interesting.
Did the B-26 design envision a more powerful R-2800, or a different engine?