I disagree. You call the Manchester a product of misguided thinking. What do you think the He-177 was? They wanted a very heavy bomber to be capable of doing dive bombing...
Come on now.
The He-177 was actually a very good design, it was just plauged with stupid problems. If they had not wanted the coupled engines the fires would not have been prone. The aircraft would have developed into a very very good Heavy Bomber.
It did not do so because of misguided thinking...
I agree, the He 177 and Manchester can be directly compared. The description of a heavy bomber powered by complex coupled engines designed to be capable of dive bombing applies to both of them. They were also both developed into fine aircraft powered by four smaller engines -. It was just that Britain dropped the dive bombing requirement fairly early on and the Lancaster ended up being mass produced.