From the US side of things,
25 February 1944.
The 15th Air Force attacked Regensburg in Germany, Graz and Klagenfurt in Austria and Pola in Italy, 235 effective, 69 non effective and 69 non sorties, 40 bombers shot down or missing, 51 damaged, 117 enemy fighters claimed shot down (63 Bf109, 29 Bf110, 10 Fw190, 13 Ju88, 2 Me210), 618.75 short tons of HE bombs dropped, 80.75 tons jettisoned. The 450th Bombardment Group 25 effective, 2 non effective and 2 non sorties, 4 bombers lost, 13 damaged. 1 Bf109 claimed shot down, one of the lost bombers was interned in Switzerland.
The 40 US bombers losses I know of, B-17 2 to collision, 18 to fighters, B-24 1 Crash, 2 to flak and fighters, 13 to fighters, 2 to flak, 2 to mechanical failure.
The 8th Air Force attacked Regensburg, Ausgburg, Furth and Stuttgart in Germany, so there was an overlap.
The Luftwaffe records are not as complete as the US ones plus there is the chance claims are incorrectly recorded against the "wrong" US Air Force. The known claims made against the 15th Air Force raids are
JG27, 12 B-17, 1 B-17 shot out for formation, 1 P-38
JG53, 1 B-17, 7 B-24
JG77, 4 B-17, 1 B-17 shot out for formation, 1 B-24
JG108, 1 B-24
ZG1, 4 B-24.