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What I don't see is hard data from anyone demonstrating that either configuration was better, given the myriad of different conditions and circumstances under which aircraft were shot down.
The only Anglo-American ace I've ever heard expressing admiration for centreline armament was Bader and that was in the context of the destructive power of the 20mm cannon firing through the spinner of the Bf 109 F.
The Bf109F2 only had a 15mm motorcannon,
The Ta-152-H was equipped with 20mm cannons in wing roots, as most of Fw-190. We could-should call those cannons 'center line' weapons?
The Ta-152-C have had additonal pair of cannons under cowling, roughly where the Fw-190s usually had MGs. So we have here a centerline battery of 4 x 20 mm and one 30 mm?
The benefits of a centerline battery, consisting of one 15-20mm and two MGs would be overweighted by brute power of a quartet of 20 mm cannons, provided the plane has engine power to carry those?